Docosahexaenoic acid ethyl esters ineffective?
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چکیده
منابع مشابه
Docosahexaenoic acid ethyl esters ineffective?
Recently in PNAS, Hoshi et al. (1) report the results of elegant studies defining the molecular basis for the blood pressure-lowering effect of omega-3 fatty acids, in particular docosahexaenoic acid (DHA). They found that DHA, when infused intravenously, activated the large-conductance Caand voltage-activated K (BK) channels in vascular smooth muscle but that the infusion of DHA ethyl esters (...
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Although alcohol abuse is known to cause an array of ethanol-induced red blood cell (RBC) abnormalities, the underlying molecular mechanisms remain poorly understood. Fatty acid ethyl esters (FAEEs) are toxic, nonoxidative ethanol metabolites that have been found in blood, plasma, and tissues. Because FAEEs have been shown to be incorporated into phospholipid bilayers, we conducted a controlled...
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INTRODUCTION Hypertriglyceridemia is an independent risk factor for coronary heart disease (CHD), according to the guidelines from the Third Report of the National Cholesterol Education Program Expert Panel on the Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (NCEP ATP III). High triglyceride (TG) levels are frequently found in combination with insulin resistance, obe...
متن کاملMeconium Fatty Acid Ethyl Esters: an Emerging Marker
Due to the relatively short half-lives of ethanol and its major metabolite, acetaldehyde, there has been intense search of more stable and reliable biological markers. Fatty acid ethyl esters (FAEE) are a group of ethanol metabolites that result from the enzymatic conjugation of free fatty acids or fatty acyl-CoA to ethanol. FAEE have been proposed as markers of recent and chronic ethanol consu...
متن کاملPrevalence of fatty acid ethyl esters in meconium specimens.
BACKGROUND Fetal alcohol syndrome (FAS), alcohol-related birth defects (ARBDs), and alcohol-related neurodevelopment disorders (ARNDs) in neonates are often the result of maternal alcohol consumption during pregnancy. Facial characteristics are associated with FAS, but ARBDs and ARNDs are more difficult to diagnose. Fetal exposure to alcohol can cause central nervous system dysfunction, pre- an...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2013
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1305038110